RIN3

Across TCGA cell cohorts, RIN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,502 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RIN3-associated GO terms across cancer lineages are Positive regulation of supramolecular fiber organization, Regulation of cell-substrate adhesion, and Regulation of cell-substrate junction organization. Each is linked with RIN3 in more than 13 cancer types. Because this analysis shows association rather than direction, both RIN3-to-partner and partner-to-RIN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of supramolecular fiber organization grouped by RIN3-low versus RIN3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIN3→partner) and Y-score (partner→RIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of supramolecular fiber organization →	+0.095	+2.284	<.001	<.001	3	14
BONE	Regulation of cell-substrate adhesion →	+0.130	+1.881	<.001	<.001	3	13
BONE	Regulation of cell-substrate junction organization →	+0.152	+2.304	<.001	<.001	3	12
BONE	Regulation of cell-matrix adhesion →	+0.149	+2.086	<.001	<.001	3	12
BREAST	Regulation of cytokine-mediated signaling pathway →	+0.077	+1.803	<.001	<.001	3	12
OVARY	Regulation of fibroblast proliferation →	+0.123	+1.576	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,502 associations by consensus.

Positive regulation of supramolecular fiber organization by RIN3 expression — BONE

Explore this box plot interactively →