RIMS4

Across TCGA patient cohorts, RIMS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,147 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RIMS4-associated proteins across cancer lineages are OSBPL3_S437, PLEC_T2735, and PLEC_T2886. Each is linked with RIMS4 in more than 4 cancer types. Because this analysis shows association rather than direction, both RIMS4-to-partner and partner-to-RIMS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIMS4 versus OSBPL3_S437 in LUAD, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS4→partner) and Y-score (partner→RIMS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OSBPL3_S437 →	-0.536	-0.441	<.001	.002	3	5
GBM	PLEC_T2735 →	-0.619	-1.217	<.001	<.001	3	5
GBM	PLEC_T2886 →	-0.619	-1.217	<.001	<.001	3	5
GBM	AZU1 →	-0.950	-0.907	<.001	.004	3	4
BRCA	CDCP1 →	-0.517	-1.948	<.001	<.001	3	4
HNSC	CRMP1 →	+0.707	+0.568	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,147 associations by consensus.

RIMS4 vs OSBPL3_S437 — LUAD

Explore this scatter interactively →