RIMS4

Across TCGA cell cohorts, RIMS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,516 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RIMS4-associated GO terms across cancer lineages are Protein-DNA complex organization, Regulation of sodium ion transmembrane transporter activity, and Positive regulation of monoatomic ion transmembrane transport. Each is linked with RIMS4 in more than 11 cancer types. Because this analysis shows association rather than direction, both RIMS4-to-partner and partner-to-RIMS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by RIMS4-low versus RIMS4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS4→partner) and Y-score (partner→RIMS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein-DNA complex organization →	+0.062	+1.374	.001	<.001	3	12
SOFT_TISSUE	Regulation of sodium ion transmembrane transporter activity →	-0.158	-1.418	.001	.007	3	11
OVARY	Positive regulation of monoatomic ion transmembrane transport →	-0.116	-1.885	<.001	<.001	3	11
SOFT_TISSUE	Negative regulation of adaptive immune response →	-0.085	-1.286	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of potassium ion transmembrane transport →	-0.163	-1.487	<.001	.005	3	10
LUNG_NSCLC_LUSC	Positive regulation of potassium ion transmembrane transport →	-0.209	-1.394	<.001	.005	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,516 associations by consensus.

Protein-DNA complex organization by RIMS4 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →