RIMS2

Across TCGA patient cohorts, RIMS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,686 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RIMS2-associated proteins across cancer lineages are RIMS2_S1347, OCRL, and PXN. Each is linked with RIMS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RIMS2-to-partner and partner-to-RIMS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIMS2 versus RIMS2_S1347 in LSCC, with a Pearson correlation of 0.91.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS2→partner) and Y-score (partner→RIMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RIMS2_S1347 →	+2.615	+3.301	<.001	<.001	3	4
HNSC	OCRL →	+0.347	+1.425	<.001	<.001	3	3
LSCC	PXN →	-0.323	-1.102	<.001	.003	3	3
UCEC	RALGAPA1 →	+0.253	+1.111	.001	.002	3	3
CCRCC	TBX2_S360 →	-0.537	-0.656	.001	<.001	3	3
BRCA	TOMM22 →	+0.264	+0.862	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,686 associations by consensus.

RIMS2 vs RIMS2_S1347 — LSCC

Explore this scatter interactively →