RIMS2

Across TCGA patient cohorts, RIMS2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,279 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RIMS2-associated genes across cancer lineages are FHL5, PNOC, and GPAT2P1. Each is linked with RIMS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMS2-to-partner and partner-to-RIMS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIMS2 versus FHL5 in HNSC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS2→partner) and Y-score (partner→RIMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FHL5 →	+0.900	+0.794	.009	.008	3	2
GBM	PNOC →	+1.058	+0.320	<.001	.001	3	2
HNSC	GPAT2P1 →	+0.346	+0.747	.001	<.001	3	2
HNSC	AMY2B →	+0.814	+0.768	.003	.004	3	2
HNSC	CCNL2P1 →	+1.095	+0.872	.008	.002	3	2
GBM	BCAS1 →	+1.872	+0.404	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,279 associations by consensus.

RIMS2 vs FHL5 — HNSC

Explore this scatter interactively →