RIMS2

Across TCGA cell cohorts, RIMS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,393 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RIMS2-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Regulation of protein modification by small protein conjugation or removal, and Protein-DNA complex assembly. Each is linked with RIMS2 in more than 10 cancer types. Because this analysis shows association rather than direction, both RIMS2-to-partner and partner-to-RIMS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by RIMS2-low versus RIMS2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS2→partner) and Y-score (partner→RIMS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of post-translational protein modification →	+0.058	+1.507	.002	.001	2	11
STOMACH	Regulation of protein modification by small protein conjugation or removal →	+0.071	+1.721	<.001	.002	3	10
STOMACH	Protein-DNA complex assembly →	+0.053	+1.178	<.001	.008	3	9
OESOPHAGUS	Spontaneous synaptic transmission →	+1.037	+1.779	.003	.004	1	11
LUNG_SCLC	Regulation of DNA replication →	+0.087	+2.105	.001	<.001	3	8
STOMACH	Protein-DNA complex organization →	+0.066	+1.794	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,393 associations by consensus.

Regulation of post-translational protein modification by RIMS2 expression — OESOPHAGUS

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