RIMKLB

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RIMKLB protein abundance is significantly associated with the RNA expression of many other genes, with 734 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RIMKLB-associated genes across cancer lineages are LINC00174, IDS, and OCA2. Each is linked with RIMKLB in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMKLB-to-partner and partner-to-RIMKLB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIMKLB versus LINC00174 in LSCC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMKLB→partner) and Y-score (partner→RIMKLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCLINC00174 →-0.616-0.518<.001.00132
LUADIDS →-0.747-0.855.003.00431
LUADOCA2 →+0.756+0.560.003.00831
LUADSULT2A1 →+0.062+0.769<.001<.00131
LUADMET →-1.147-0.623.008.00231
LUADABHD11 →-0.870-1.066<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 734 associations by consensus.

RIMKLB vs LINC00174 — LSCC

Per-sample scatter of RIMKLB vs LINC00174 in LSCC (Pearson r = -0.47).

Explore this scatter interactively →

Exploration