RIMKLB

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RIMKLB mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RIMKLB-associated genes across cancer lineages are OR10K2, PABPC1L2A, and OR10T2. Each is linked with RIMKLB in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMKLB-to-partner and partner-to-RIMKLB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K2 grouped by RIMKLB-low versus RIMKLB-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMKLB→partner) and Y-score (partner→RIMKLB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTOR10K2 →+0.063+5.781<.001.00131
BREASTPABPC1L2A →+0.083+5.169<.001.00531
BREASTOR10T2 →+0.183+5.781<.001.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10K2 by RIMKLB expression — BREAST

Box plot of OR10K2 in RIMKLB-low vs RIMKLB-high samples in BREAST.

Explore this box plot interactively →

Exploration