RIMBP3B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RIMBP3B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RIMBP3B-associated genes across cancer lineages are RNASE11 and FGF7P4. Each is linked with RIMBP3B in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMBP3B-to-partner and partner-to-RIMBP3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASE11 grouped by RIMBP3B-low versus RIMBP3B-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMBP3B→partner) and Y-score (partner→RIMBP3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNASE11 →+0.024+7.741<.001.00931
COADFGF7P4 →+0.139+7.741<.001.00931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

RNASE11 by RIMBP3B expression — COAD

Box plot of RNASE11 in RIMBP3B-low vs RIMBP3B-high samples in COAD.

Explore this box plot interactively →

Exploration