RIMBP2

Across TCGA cell cohorts, RIMBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,546 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RIMBP2-associated GO terms across cancer lineages are Regulation of T cell differentiation, Regulation of endocrine process, and Nucleoside triphosphate biosynthetic process. Each is linked with RIMBP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both RIMBP2-to-partner and partner-to-RIMBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of T cell differentiation grouped by RIMBP2-low versus RIMBP2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMBP2→partner) and Y-score (partner→RIMBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of T cell differentiation →	+0.048	+1.409	.004	<.001	3	6
LUNG_SCLC	Regulation of endocrine process →	-0.091	-2.175	.001	.005	3	6
BLOOD_Lymphoma	Nucleoside triphosphate biosynthetic process →	+0.088	+0.756	<.001	.006	3	5
BLOOD_Leukemia	Glycolipid catabolic process →	-0.070	-0.658	<.001	.001	3	5
BLOOD_Lymphoma	Ribonucleoside triphosphate biosynthetic process →	+0.101	+1.086	<.001	.002	3	5
BONE	Integrin activation →	-0.178	-1.821	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,546 associations by consensus.

Regulation of T cell differentiation by RIMBP2 expression — LARGE_INTESTINE

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