RIMBP2

Across TCGA cell cohorts, RIMBP2 mutation is significantly associated with the RNA expression of many other genes, with 1,012 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RIMBP2-associated genes across cancer lineages are KRTAP2-1, OR5P2, and EPX. Each is linked with RIMBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMBP2-to-partner and partner-to-RIMBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP2-1 grouped by RIMBP2-low versus RIMBP2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMBP2→partner) and Y-score (partner→RIMBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	KRTAP2-1 →	+0.160	+4.417	<.001	.004	3	2
BLOOD_Lymphoma	OR5P2 →	+0.028	+4.867	<.001	.009	3	2
LUNG_NSCLC_LUAD	EPX →	+0.029	+2.918	.004	.003	3	2
LARGE_INTESTINE	CBY1 →	+0.698	+2.451	<.001	<.001	3	2
LARGE_INTESTINE	GNPNAT1 →	+0.618	+1.936	<.001	.005	3	2
LARGE_INTESTINE	SUFU →	+0.449	+1.850	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,012 associations by consensus.

KRTAP2-1 by RIMBP2 expression — SOFT_TISSUE

Explore this box plot interactively →