RILPL1

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RILPL1 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RILPL1-associated genes across cancer lineages are eEF2, GAPDH, and EGFR_pY1068. Each is linked with RILPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RILPL1-to-partner and partner-to-RILPL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RILPL1→partner) and Y-score (partner→RILPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeEF2 →+0.388+2.415.007.00332
UCECGAPDH →+0.526+2.584.014.01032
UCECEGFR_pY1068 →-0.260-2.415.010.00331
UCECA-Raf_pS299 →-0.112-3.321.019.00931
UCECINPP4B →-0.307-2.000.018.03031
UCECKu80 →+0.192+2.428.043.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration