Across TCGA cell cohorts, RILPL1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RILPL1-associated genes across cancer lineages are DPT, WFDC12, and DEFB4A. Each is linked with RILPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RILPL1-to-partner and partner-to-RILPL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RILPL1→partner) and Y-score (partner→RILPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DPT →	+1.409	+3.769	<.001	.008	3	1
BLOOD_Leukemia	WFDC12 →	+0.198	+3.874	<.001	.005	3	1
BLOOD_Leukemia	DEFB4A →	+0.096	+4.269	.001	.002	3	1
BLOOD_Leukemia	DEFB108B →	+0.129	+4.269	<.001	.002	3	1
BLOOD_Leukemia	GUCA2A →	+0.031	+4.384	<.001	.006	3	1
BLOOD_Leukemia	SLC5A8 →	+0.111	+4.786	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

RILPL1 survival (RNA) · tumor vs normal (RNA) · all RILPL1 data types