RILP

Across TCGA pan-cancer cohorts, RILP mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RILP data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RILP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RILP expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where RILP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.917	0.430	.018	12	view →
CCRCC	DFS	Tertile	All	0.880	0.624	.005	11	view →
HNSC	OS	Median	All	0.840	0.627	.012	5	view →
LUAD	DFS	Median	II,III,IV	1.000	0.798	.015	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RILP–UCEC (DFS)

Open the UCEC breakdown →