RILP

Across TCGA patient cohorts, RILP mutation is significantly associated with the RNA expression of many other genes, with 194 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RILP-associated genes across cancer lineages are RNU6-1066P, RN7SL107P, and SMIM28. Each is linked with RILP in more than 1 cancer types. Because this analysis shows association rather than direction, both RILP-to-partner and partner-to-RILP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1066P grouped by RILP-low versus RILP-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RILP→partner) and Y-score (partner→RILP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1066P →	+0.201	+7.930	<.001	.008	3	2
SKCM	RN7SL107P →	+0.210	+5.771	<.001	.003	3	2
UCEC	SMIM28 →	+0.358	+2.955	.001	.007	3	2
UCEC	MIR3180-5 →	+0.394	+3.562	<.001	.004	3	2
UCEC	RNU2-61P →	+0.515	+3.884	<.001	.002	3	2
UCEC	DPY19L4P2 →	+0.142	+2.976	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 194 associations by consensus.

RNU6-1066P by RILP expression — LUAD

Explore this box plot interactively →