RILP

Across TCGA cell cohorts, RILP mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RILP-associated genes across cancer lineages are BPIFB6, ZBBX, and KCNU1. Each is linked with RILP in more than 1 cancer types. Because this analysis shows association rather than direction, both RILP-to-partner and partner-to-RILP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by RILP-low versus RILP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RILP→partner) and Y-score (partner→RILP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	ZBBX →	+0.146	+3.777	<.001	.007	3	1
LARGE_INTESTINE	KCNU1 →	+0.050	+3.930	<.001	.003	3	1
LARGE_INTESTINE	KRTAP7-1 →	+0.048	+4.437	<.001	.004	3	1
LARGE_INTESTINE	INSRR →	+0.039	+4.584	<.001	.003	3	1
LARGE_INTESTINE	NOVA2 →	+0.323	+3.898	<.001	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

BPIFB6 by RILP expression — LARGE_INTESTINE

Explore this box plot interactively →