RIIAD1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RIIAD1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIIAD1-associated genes across cancer lineages are Hepatocytes, Pericytes, and Myocytes. Each is linked with RIIAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIIAD1-to-partner and partner-to-RIIAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hepatocytes grouped by RIIAD1-low versus RIIAD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIIAD1→partner) and Y-score (partner→RIIAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECHepatocytes →+0.016+2.828.013.03631
UCECPericytes →+0.036+2.113.028.04431
UCECMyocytes →+0.048+2.850.014.03521
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Hepatocytes by RIIAD1 expression — UCEC

Box plot of Hepatocytes in RIIAD1-low vs RIIAD1-high samples in UCEC.

Explore this box plot interactively →

Exploration