RIIAD1

Across TCGA cell cohorts, RIIAD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,113 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RIIAD1-associated GO terms across cancer lineages are Natural killer cell activation involved in immune response, Blood coagulation, intrinsic pathway, and Base-excision repair, gap-filling. Each is linked with RIIAD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both RIIAD1-to-partner and partner-to-RIIAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Natural killer cell activation involved in immune response grouped by RIIAD1-low versus RIIAD1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIIAD1→partner) and Y-score (partner→RIIAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Natural killer cell activation involved in immune response →	+0.228	+0.549	.001	.007	3	5
BREAST	Blood coagulation, intrinsic pathway →	-0.218	-0.817	.001	.002	3	5
BREAST	Base-excision repair, gap-filling →	+0.098	+0.826	<.001	.001	3	5
LUNG_SCLC	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.060	+1.331	<.001	<.001	3	5
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.052	+0.913	<.001	<.001	3	5
STOMACH	Lactation →	+0.139	+0.230	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,113 associations by consensus.

Natural killer cell activation involved in immune response by RIIAD1 expression — LARGE_INTESTINE

Explore this box plot interactively →