RIDA

Across TCGA pan-cancer cohorts, RIDA mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated RIDA data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RIDA mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RIDA expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

COAD, CCRCC, and HNSC are the cancer types where RIDA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.883	.023	24	view →
CCRCC	DFS	Median	All	0.919	0.554	.005	23	view →
HNSC	DFS	Tertile	All	1.000	0.317	.028	7	view →
GBM	OS	Quartile	All	0.174	0.621	.006	7	view →
PDAC	OS	Quartile	II,III,IV	1.000	0.771	.039	4	view →
LUAD	DFS	Tertile	All	0.571	1.000	.009	3	view →
LSCC	OS	Median	All	0.931	0.797	.021	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RIDA–COAD (DFS)

Open the COAD breakdown →