RIC8A

Across TCGA patient cohorts, RIC8A protein abundance is significantly associated with the RNA expression of many other genes, with 9,765 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible RIC8A-associated genes across cancer lineages are TIMM10B, NUP98, and SIRT3. Each is linked with RIC8A in more than 5 cancer types. Because this analysis shows association rather than direction, both RIC8A-to-partner and partner-to-RIC8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIC8A versus TIMM10B in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIC8A→partner) and Y-score (partner→RIC8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TIMM10B →	+0.501	+0.430	<.001	.007	3	6
COAD	NUP98 →	+0.542	+0.199	<.001	<.001	3	6
COAD	SIRT3 →	+0.459	+0.185	<.001	<.001	3	6
BRCA	GATD1 →	+0.513	+0.149	<.001	<.001	3	6
BRCA	RRP8 →	+0.392	+0.177	<.001	<.001	3	5
COAD	DENND2B →	+0.484	+0.158	.004	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,765 associations by consensus.

RIC8A vs TIMM10B — OV

Explore this scatter interactively →