RIC8A

Across TCGA cell cohorts, RIC8A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,584 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RIC8A-associated GO terms across cancer lineages are Regulation of anaphase-promoting complex-dependent catabolic process, Telomere localization, and Telomere tethering at nuclear periphery. Each is linked with RIC8A in more than 14 cancer types. Because this analysis shows association rather than direction, both RIC8A-to-partner and partner-to-RIC8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of anaphase-promoting complex-dependent catabolic process grouped by RIC8A-low versus RIC8A-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIC8A→partner) and Y-score (partner→RIC8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.142	+0.683	<.001	.001	3	15
LUNG_NSCLC_LUAD	Telomere localization →	+0.185	+0.627	<.001	<.001	3	15
OVARY	Telomere tethering at nuclear periphery →	+0.149	+0.779	<.001	<.001	3	15
LIVER	Protein localization to endosome →	+0.187	+0.987	.005	.005	3	15
LIVER	Regulation of protein K48-linked ubiquitination →	+0.154	+1.277	.001	<.001	3	15
LUNG_NSCLC_LUSC	Negative regulation of cilium assembly →	+0.088	+0.977	.001	.005	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,584 associations by consensus.

Regulation of anaphase-promoting complex-dependent catabolic process by RIC8A expression — BLOOD_Lymphoma

Explore this box plot interactively →