RIC3

Across TCGA cell cohorts, RIC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,246 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible RIC3-associated GO terms across cancer lineages are Cytoplasmic translation, Electron transport chain, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with RIC3 in more than 7 cancer types. Because this analysis shows association rather than direction, both RIC3-to-partner and partner-to-RIC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by RIC3-low versus RIC3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIC3→partner) and Y-score (partner→RIC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Cytoplasmic translation →	+0.092	+1.916	<.001	.002	3	8
BLOOD_Lymphoma	Electron transport chain →	+0.062	+0.933	<.001	.005	3	8
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.112	+1.001	<.001	.002	3	8
BLOOD_Lymphoma	RNA splicing, via transesterification reactions →	+0.033	+0.678	.003	.004	3	8
LUNG_SCLC	Aerobic respiration →	+0.092	+2.011	.001	.003	3	8
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.077	+2.267	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,246 associations by consensus.

Cytoplasmic translation by RIC3 expression — LUNG_SCLC

Explore this box plot interactively →