RIBC2

Across TCGA cell cohorts, RIBC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,960 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RIBC2-associated GO terms across cancer lineages are Cell cycle checkpoint signaling, Purine nucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with RIBC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both RIBC2-to-partner and partner-to-RIBC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle checkpoint signaling grouped by RIBC2-low versus RIBC2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIBC2→partner) and Y-score (partner→RIBC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cell cycle checkpoint signaling →	+0.070	+0.984	.004	.008	3	10
UPPER_AERODIGESTIVE_TRACT	Purine nucleoside triphosphate biosynthetic process →	+0.074	+1.138	.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Purine ribonucleoside triphosphate biosynthetic process →	+0.074	+1.138	.001	.001	3	10
STOMACH	Ribonucleoside triphosphate biosynthetic process →	+0.077	+1.528	.007	.004	3	9
BONE	Mitotic DNA replication →	+0.219	+1.762	.006	<.001	2	10
BONE	Negative regulation of cell cycle process →	+0.051	+1.136	.005	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,960 associations by consensus.

Cell cycle checkpoint signaling by RIBC2 expression — BONE

Explore this box plot interactively →