RIBC1

Across TCGA patient cohorts, RIBC1 mutation is significantly associated with the RNA expression of many other genes, with 3,260 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIBC1-associated genes across cancer lineages are SEPTIN14P19, DPPA5P1, and RNU4-16P. Each is linked with RIBC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIBC1-to-partner and partner-to-RIBC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEPTIN14P19 grouped by RIBC1-low versus RIBC1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIBC1→partner) and Y-score (partner→RIBC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEPTIN14P19 →	+0.059	+5.822	<.001	.003	3	2
UCEC	DPPA5P1 →	+0.222	+2.206	<.001	.001	3	2
UCEC	RNU4-16P →	+0.219	+2.415	.006	.002	3	2
UCEC	MIR1298 →	+0.068	+4.896	<.001	.001	3	2
UCEC	RN7SL354P →	+0.254	+2.084	<.001	.001	3	2
UCEC	RN7SL654P →	+0.107	+2.694	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,260 associations by consensus.

SEPTIN14P19 by RIBC1 expression — HNSC

Explore this box plot interactively →