RHPN2

Across TCGA cell cohorts, RHPN2 mutation is significantly associated with the RNA expression of many other genes, with 257 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHPN2-associated genes across cancer lineages are CADM4, SCD5, and EOMES. Each is linked with RHPN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHPN2-to-partner and partner-to-RHPN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CADM4 grouped by RHPN2-low versus RHPN2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHPN2→partner) and Y-score (partner→RHPN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CADM4 →	+1.082	+3.215	.001	.005	3	2
BLOOD_Leukemia	SCD5 →	+1.537	+3.489	.003	.001	3	2
LARGE_INTESTINE	EOMES →	+0.510	+3.726	<.001	<.001	3	2
LARGE_INTESTINE	C12orf57 →	+0.773	+2.502	.003	.005	3	2
LARGE_INTESTINE	NRTN →	+0.770	+3.252	.001	.002	3	2
LARGE_INTESTINE	CYB5D1 →	+0.980	+3.252	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 257 associations by consensus.

CADM4 by RHPN2 expression — BLOOD_Leukemia

Explore this box plot interactively →