RHPN1

Across TCGA patient cohorts, RHPN1 mutation is significantly associated with the RNA expression of many other genes, with 2,847 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHPN1-associated genes across cancer lineages are CHAF1A, RNA5SP105, and RPL23AP4. Each is linked with RHPN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both RHPN1-to-partner and partner-to-RHPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHAF1A grouped by RHPN1-low versus RHPN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHPN1→partner) and Y-score (partner→RHPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHAF1A →	+0.777	+2.684	<.001	<.001	3	3
SKCM	RNA5SP105 →	+0.247	+4.634	<.001	.003	3	3
READ	RPL23AP4 →	+0.171	+5.039	<.001	.008	3	2
UCEC	HIRIP3 →	+0.534	+2.673	<.001	<.001	3	2
UCEC	SAR1B →	+0.508	+3.321	<.001	<.001	3	2
UCEC	BUB3 →	+0.517	+2.775	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,847 associations by consensus.

CHAF1A by RHPN1 expression — UCEC

Explore this box plot interactively →