RHPN1

Across TCGA cell cohorts, RHPN1 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHPN1-associated genes across cancer lineages are ADAM30, OR10R2, and LY6G6F. Each is linked with RHPN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHPN1-to-partner and partner-to-RHPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM30 grouped by RHPN1-low versus RHPN1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHPN1→partner) and Y-score (partner→RHPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADAM30 →	+0.007	+3.762	<.001	.007	3	2
BLOOD_Leukemia	OR10R2 →	+1.230	+3.288	<.001	<.001	3	2
URINARY_TRACT	LY6G6F →	+0.040	+5.087	<.001	.004	3	1
LUNG_NSCLC_LUSC	USP17L15 →	+0.006	+4.643	<.001	.008	3	1
OVARY	USP17L13 →	+0.013	+5.807	<.001	.001	3	1
OVARY	USP17L17 →	+0.013	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

ADAM30 by RHPN1 expression — BLOOD_Leukemia

Explore this box plot interactively →