RHOXF1

Across TCGA patient cohorts, RHOXF1 mutation is significantly associated with the RNA expression of many other genes, with 760 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHOXF1-associated genes across cancer lineages are OR10J6P, RNU6-1169P, and COX6CP7. Each is linked with RHOXF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOXF1-to-partner and partner-to-RHOXF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10J6P grouped by RHOXF1-low versus RHOXF1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOXF1→partner) and Y-score (partner→RHOXF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	OR10J6P →	+0.074	+4.706	.003	.007	3	2
LUSC	RNU6-1169P →	+0.557	+4.187	<.001	.009	3	2
LUAD	COX6CP7 →	+0.169	+4.217	<.001	.002	3	2
LUAD	MYO5BP1 →	+0.036	+4.074	.003	.001	3	2
UCEC	MIR4648 →	+0.734	+1.954	<.001	.005	3	2
UCEC	PPP1R37 →	+0.399	+2.254	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 760 associations by consensus.

OR10J6P by RHOXF1 expression — LUSC

Explore this box plot interactively →