RHOXF1

Across TCGA cell cohorts, RHOXF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,419 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible RHOXF1-associated GO terms across cancer lineages are Intracellular sphingolipid homeostasis, Regulation of mitophagy, and Regulation of macroautophagy. Each is linked with RHOXF1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RHOXF1-to-partner and partner-to-RHOXF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular sphingolipid homeostasis grouped by RHOXF1-low versus RHOXF1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOXF1→partner) and Y-score (partner→RHOXF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Intracellular sphingolipid homeostasis →	+0.076	+0.046	.007	.001	3	7
LUNG_SCLC	Regulation of mitophagy →	+0.063	+0.418	.007	.002	3	6
OVARY	Regulation of macroautophagy →	+0.043	+0.127	<.001	.001	3	6
OVARY	Methylglyoxal metabolic process →	+0.087	+0.115	<.001	.001	3	5
OVARY	Cellular detoxification of aldehyde →	+0.115	+0.164	<.001	<.001	3	5
PANCREAS	Sister chromatid biorientation →	-0.088	-0.141	.007	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,419 associations by consensus.

Intracellular sphingolipid homeostasis by RHOXF1 expression — SOFT_TISSUE

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