RHOXF1-AS1

Across TCGA pan-cancer cohorts, RHOXF1-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RHOXF1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where RHOXF1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types RHOXF1-AS1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, THCA, and BRCA are the cancer types where RHOXF1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RHOXF1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−2.431	<.001	9	view →
THCA	Female	All	−1.242	<.001	9	view →
BRCA	All	III,IV	−2.582	<.001	8	view →
LUSC	Male	II,III,IV	−2.371	<.001	7	view →
KIRC	Male	II,III,IV	−0.297	<.001	6	view →
LIHC	All	All	+0.227	.004	4	view →
COAD	Male	All	−0.215	.007	4	view →
HNSC	All	II,III,IV	−0.655	.007	3	view →
KICH	All	All	−0.409	.011	2	view →
PRAD	All	All	−0.232	.003	2	view →
CHOL	All	All	+0.625	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RHOXF1-AS1–LUAD

Open the LUAD breakdown →