RHOV

Across TCGA pan-cancer cohorts, RHOV mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated RHOV data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RHOV mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated RHOV expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC are the cancer types where RHOV mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	III,IV	0.956	0.404	.022	4	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

RHOV–HNSC (OS)

Open the HNSC breakdown →