RHOV

Across TCGA cell cohorts, RHOV mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RHOV-associated genes across cancer lineages are MS4A4A and CLPSL1. Each is linked with RHOV in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOV-to-partner and partner-to-RHOV results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A4A grouped by RHOV-low versus RHOV-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOV→partner) and Y-score (partner→RHOV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MS4A4A →	+0.242	+3.678	<.001	.009	3	1
LARGE_INTESTINE	CLPSL1 →	+0.158	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MS4A4A by RHOV expression — LARGE_INTESTINE

Explore this box plot interactively →