RHOU

Across TCGA cell cohorts, RHOU mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHOU-associated genes across cancer lineages are TSHB, OR10T2, and OR10R2. Each is linked with RHOU in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOU-to-partner and partner-to-RHOU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TSHB grouped by RHOU-low versus RHOU-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOU→partner) and Y-score (partner→RHOU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TSHB →	+0.128	+4.276	.003	.007	3	1
BLOOD_Leukemia	OR10T2 →	+0.548	+4.276	.008	.007	3	1
BLOOD_Leukemia	OR10R2 →	+1.286	+4.551	.006	.004	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
BLOOD_Lymphoma	R3HDML →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	BANF2 →	+0.047	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

TSHB by RHOU expression — BLOOD_Leukemia

Explore this box plot interactively →