RHOU

Across TCGA cell cohorts, RHOU mutation is significantly associated with the mutation status of many other genes, with 656 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHOU-associated genes across cancer lineages are MTA2, SPHKAP, and CNOT4. Each is linked with RHOU in more than 2 cancer types. Because this analysis shows association rather than direction, both RHOU-to-partner and partner-to-RHOU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTA2 grouped by RHOU-low versus RHOU-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOU→partner) and Y-score (partner→RHOU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MTA2 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	SPHKAP →	+4.014	+4.969	.008	.008	1	3
BLOOD_Lymphoma	CNOT4 →	+6.014	+6.014	.001	.001	1	3
BLOOD_Lymphoma	TRIM24 →	+6.014	+6.014	.001	.001	1	2
BLOOD_Lymphoma	BARHL1 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	EML2 →	+6.014	+6.014	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 656 associations by consensus.

MTA2 by RHOU expression — BLOOD_Lymphoma

Explore this box plot interactively →