RHOT2

Across TCGA cell cohorts, RHOT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,313 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RHOT2-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Metanephric proximal tubule development. Each is linked with RHOT2 in more than 17 cancer types. Because this analysis shows association rather than direction, both RHOT2-to-partner and partner-to-RHOT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by RHOT2-low versus RHOT2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOT2→partner) and Y-score (partner→RHOT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.208	+1.247	<.001	<.001	3	18
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.157	+1.078	<.001	<.001	3	17
STOMACH	Metanephric proximal tubule development →	+0.237	+0.574	.001	.006	3	16
BONE	Calcium-independent cell-matrix adhesion →	+0.224	+1.418	<.001	<.001	3	15
LUNG_SCLC	Late viral transcription →	+0.161	+0.642	<.001	.004	3	15
BONE	Negative regulation of translational initiation →	+0.099	+0.907	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,313 associations by consensus.

Pre-mRNA catabolic process by RHOT2 expression — BONE

Explore this box plot interactively →