RHOT2

Across TCGA cell cohorts, RHOT2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,658 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RHOT2-associated genes across cancer lineages are MECP2, ZBED6CL, and TMEM120A. Each is linked with RHOT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both RHOT2-to-partner and partner-to-RHOT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOT2 versus MECP2 in OESOPHAGUS, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOT2→partner) and Y-score (partner→RHOT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MECP2 →	-0.735	-0.885	.005	.002	3	4
LUNG_SCLC	ZBED6CL →	+1.603	+0.665	.001	.003	3	4
SKIN	TMEM120A →	+0.832	+0.617	<.001	.002	3	4
BLOOD_Leukemia	SLC20A1 →	-0.671	-0.514	.005	.003	3	4
STOMACH	BRD1 →	+0.965	+1.420	.005	.004	3	3
STOMACH	STX16 →	+0.773	+1.313	.008	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,658 associations by consensus.

RHOT2 vs MECP2 — OESOPHAGUS

Explore this scatter interactively →