RHOT1P3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RHOT1P3 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHOT1P3-associated genes across cancer lineages are Platelets, Myocytes, and pDC. Each is linked with RHOT1P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOT1P3-to-partner and partner-to-RHOT1P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by RHOT1P3-low versus RHOT1P3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOT1P3→partner) and Y-score (partner→RHOT1P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPlatelets →+0.037+2.148<.001.04132
UCECMyocytes →+0.048+2.850.016.03531
UCECpDC →+0.069+2.818.021.03711
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Platelets by RHOT1P3 expression — UCEC

Box plot of Platelets in RHOT1P3-low vs RHOT1P3-high samples in UCEC.

Explore this box plot interactively →

Exploration