Across TCGA pan-cancer cohorts, RHOT1P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of RHOT1P2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where RHOT1P2 RNA is repressed in tumor relative to normal tissue. In most cancer types RHOT1P2 is over-expressed in tumor, although a few such as HNSC and KICH show the opposite, repressed pattern.

HNSC, KICH, and READ are the cancer types where RHOT1P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RHOT1P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	−1.090	<.001	9	view →
KICH	All	II,III,IV	−0.174	<.001	6	view →
READ	All	III,IV	+0.475	<.001	2	view →
STAD	Female	III,IV	−0.765	.043	1	view →
COAD	Male	IV	−0.266	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: RHOT1P2 RNA expression & survival · all RHOT1P2 data types