RHOT1

Across TCGA patient cohorts, RHOT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,188 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RHOT1-associated proteins across cancer lineages are NF1, ZNF830, and LIG3. Each is linked with RHOT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RHOT1-to-partner and partner-to-RHOT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOT1 versus NF1 in LSCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOT1→partner) and Y-score (partner→RHOT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NF1 →	+0.458	+0.629	<.001	<.001	3	6
LSCC	ZNF830 →	+0.307	+0.521	<.001	<.001	3	6
LSCC	LIG3 →	+0.546	+0.675	<.001	<.001	3	6
LSCC	XRCC1 →	+0.364	+0.545	<.001	<.001	3	5
BRCA	TAF15 →	+0.397	+0.469	<.001	.005	3	5
BRCA	CASP10 →	-0.599	-0.552	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,188 associations by consensus.

RHOT1 vs NF1 — LSCC

Explore this scatter interactively →