RHOT1

Across TCGA patient cohorts, RHOT1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,362 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RHOT1-associated genes across cancer lineages are GIMAP6, GIMAP7, and IL18RAP. Each is linked with RHOT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both RHOT1-to-partner and partner-to-RHOT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOT1 versus GIMAP6 in BRCA, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOT1→partner) and Y-score (partner→RHOT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GIMAP6 →	-0.678	-0.278	<.001	.002	3	6
UCEC	GIMAP7 →	-1.145	-0.285	<.001	<.001	3	6
HNSC	IL18RAP →	-0.777	-0.208	.002	<.001	3	6
COAD	RARRES1 →	-1.284	-0.254	<.001	<.001	3	6
BRCA	IGLV3-25 →	-2.429	-0.317	.001	.001	3	6
HNSC	FBXL20 →	+0.720	+0.245	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,362 associations by consensus.

RHOT1 vs GIMAP6 — BRCA

Explore this scatter interactively →