RHOT1

Across TCGA cell cohorts, RHOT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,352 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHOT1-associated GO terms across cancer lineages are Establishment of mitochondrion localization, microtubule-mediated, Mitochondrion transport along microtubule, and Mitochondrial outer membrane permeabilization involved in programmed cell death. Each is linked with RHOT1 in more than 14 cancer types. Because this analysis shows association rather than direction, both RHOT1-to-partner and partner-to-RHOT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of mitochondrion localization, microtubule-mediated grouped by RHOT1-low versus RHOT1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOT1→partner) and Y-score (partner→RHOT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Establishment of mitochondrion localization, microtubule-mediated →	+0.112	+0.586	<.001	.001	3	15
LIVER	Mitochondrion transport along microtubule →	+0.112	+0.586	<.001	.001	3	15
LUNG_NSCLC_LUSC	Mitochondrial outer membrane permeabilization involved in programmed cell death →	+0.128	+0.696	.007	.003	3	13
LIVER	Establishment of mitochondrion localization →	+0.101	+0.722	<.001	.001	3	13
LUNG_SCLC	Mitochondrial outer membrane permeabilization →	+0.164	+0.781	<.001	<.001	3	12
LUNG_SCLC	Positive regulation of mitochondrial membrane permeability involved in apoptotic process →	+0.119	+0.563	<.001	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,352 associations by consensus.

Establishment of mitochondrion localization, microtubule-mediated by RHOT1 expression — LIVER

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