RHOQP2

Across TCGA pan-cancer cohorts, RHOQP2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RHOQP2’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where RHOQP2 RNA is repressed in tumor relative to normal tissue. In most cancer types RHOQP2 is over-expressed in tumor, although a few such as BLCA and BRCA show the opposite, repressed pattern.

BLCA, BRCA, and LUAD are the cancer types where RHOQP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RHOQP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	III,IV	−1.052	.001	8	view →
BRCA	All	III,IV	−0.746	<.001	6	view →
LUAD	All	All	−0.234	.001	6	view →
HNSC	Female	IV	+0.613	.006	4	view →
KICH	All	II,III,IV	−0.386	.003	4	view →
LIHC	All	All	+0.142	.004	3	view →
PAAD	All	All	−0.647	.049	2	view →
UCEC	All	All	−0.478	.001	2	view →
CHOL	All	All	+0.404	.007	2	view →
PRAD	All	All	−0.322	<.001	2	view →
THCA	All	All	−0.222	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RHOQP2–BLCA

Open the BLCA breakdown →