RHOQ-AS1

Across TCGA pan-cancer cohorts, RHOQ-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated RHOQ-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RHOQ-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RHOQ-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and BLCA show a favorable association.

KIRC, THCA, and LGG are the cancer types where RHOQ-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.536	0.707	<.001	108	view →
THCA	OS	Median	II,III,IV	0.745	0.961	<.001	62	view →
LGG	DFS	Median	All	0.297	0.489	<.001	54	view →
OV	DFS	Tertile	IV	0.241	0.485	.016	34	view →
LIHC	OS	Median	All	0.609	0.784	<.001	31	view →
ACC	OS	Median	All	0.940	0.423	.001	25	view →
MESO	OS	Median	II,III,IV	0.296	0.750	.002	23	view →
LUSC	DFS	Median	II,III,IV	0.522	0.684	.004	21	view →
BLCA	OS	Tertile	All	0.560	0.348	.008	20	view →
UCS	DFS	Tertile	IV	0.942	0.364	.024	18	view →
UVM	DFS	Quartile	III,IV	0.171	0.785	.008	17	view →
STAD	DFS	Quartile	All	0.404	0.591	.004	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

RHOQ-AS1–KIRC (DFS)

Open the KIRC breakdown →