RHOG

Across TCGA pan-cancer cohorts, RHOG mass-spec protein is linked to patient survival in 9 of 34 cancer types, making it a survival-associated RHOG data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RHOG mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RHOG expression acts as an unfavorable survival marker, although some lineages such as OV and LUAD show a favorable association.

COAD, UCEC, and CCRCC are the cancer types where RHOG mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	III,IV	0.790	1.000	.030	54	view →
UCEC	DFS	Tertile	All	0.729	0.956	.014	20	view →
CCRCC	OS	Median	II,III,IV	0.454	1.000	.014	14	view →
PDAC	DFS	Quartile	III,IV	0.130	0.442	.010	8	view →
HNSC	DFS	Tertile	All	0.907	1.000	.009	7	view →
OV	DFS	Tertile	All	1.000	0.820	.028	4	view →
LUAD	DFS	Quartile	All	0.773	0.479	.018	4	view →
GBM	OS	Median	All	0.412	0.652	.005	3	view →
LSCC	DFS	Median	II,III,IV	0.570	0.817	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

RHOG–COAD (DFS)

Open the COAD breakdown →