RHOG

Across TCGA cell cohorts, RHOG RNA expression is significantly associated with the go_rna of many other GO terms, with 5,071 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RHOG-associated GO terms across cancer lineages are Actin filament depolymerization, Positive regulation of cyclase activity, and Telomere localization. Each is linked with RHOG in more than 13 cancer types. Because this analysis shows association rather than direction, both RHOG-to-partner and partner-to-RHOG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament depolymerization grouped by RHOG-low versus RHOG-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOG→partner) and Y-score (partner→RHOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.247	+0.995	<.001	<.001	3	14
LIVER	Positive regulation of cyclase activity →	+0.224	+1.085	.001	<.001	3	13
LUNG_NSCLC_LUAD	Telomere localization →	+0.193	+0.894	<.001	<.001	3	13
BONE	Actin filament organization →	+0.111	+0.946	<.001	<.001	3	12
BONE	PML body organization →	+0.225	+1.211	<.001	<.001	3	12
LUNG_SCLC	Enamel mineralization →	+0.989	+0.747	.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,071 associations by consensus.

Actin filament depolymerization by RHOG expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →