RHOF

Across TCGA patient cohorts, RHOF protein abundance is significantly associated with the RNA expression of many other genes, with 12,938 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RHOF-associated genes across cancer lineages are PTAFR, EPSTI1, and PTPN22. Each is linked with RHOF in more than 5 cancer types. Because this analysis shows association rather than direction, both RHOF-to-partner and partner-to-RHOF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOF versus PTAFR in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOF→partner) and Y-score (partner→RHOF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PTAFR →	+0.935	+0.590	.004	<.001	3	6
COAD	EPSTI1 →	+1.330	+0.628	<.001	<.001	3	5
BRCA	PTPN22 →	+0.823	+0.441	<.001	.001	3	5
BRCA	OASL →	+1.416	+0.490	<.001	<.001	3	5
BRCA	BCL2A1 →	+1.522	+0.486	<.001	<.001	3	5
BRCA	GZMA →	+1.271	+0.386	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,938 associations by consensus.

RHOF vs PTAFR — UCEC

Explore this scatter interactively →