RHOF

Across TCGA patient cohorts, RHOF mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible RHOF-associated genes across cancer lineages are Astrocytes and Class-switched memory B-cells. Each is linked with RHOF in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOF-to-partner and partner-to-RHOF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Astrocytes grouped by RHOF-low versus RHOF-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOF→partner) and Y-score (partner→RHOF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Astrocytes →	+0.164	+5.479	<.001	.043	3	1
UCEC	Class-switched memory B-cells →	-0.064	-3.169	.041	.020	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Astrocytes by RHOF expression — LIHC

Explore this box plot interactively →