RHOF

Across TCGA cell cohorts, RHOF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,014 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RHOF-associated GO terms across cancer lineages are ERBB signaling pathway, Actin filament capping, and Cellular response to mechanical stimulus. Each is linked with RHOF in more than 8 cancer types. Because this analysis shows association rather than direction, both RHOF-to-partner and partner-to-RHOF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERBB signaling pathway grouped by RHOF-low versus RHOF-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOF→partner) and Y-score (partner→RHOF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ERBB signaling pathway →	+0.051	+1.216	.005	<.001	3	9
PANCREAS	Actin filament capping →	+0.143	+0.982	.001	.009	3	9
PANCREAS	Cellular response to mechanical stimulus →	+0.073	+1.183	.003	.003	3	9
KIDNEY	Positive regulation of NK T cell proliferation →	+1.117	+1.853	.006	.005	3	9
OESOPHAGUS	Cellular response to external stimulus →	+0.075	+2.193	.002	<.001	2	9
OVARY	Viral release from host cell →	+0.096	+1.571	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,014 associations by consensus.

ERBB signaling pathway by RHOF expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →