RHOD

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RHOD mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated RHOD data layer compared with 24 for mass-spec protein.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher RHOD mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated RHOD expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC and HNSC are the cancer types where RHOD mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSMedianII,III,IV0.6460.261.00324view →
HNSCDFSMedianAll0.7430.556.01714view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

RHOD–PDAC (DFS)

Kaplan–Meier survival curve for RHOD mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration