RHOBTB2

Across TCGA cell cohorts, RHOBTB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,291 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RHOBTB2-associated GO terms across cancer lineages are Endosomal transport, Schwann cell differentiation, and Vacuole fusion. Each is linked with RHOBTB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both RHOBTB2-to-partner and partner-to-RHOBTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by RHOBTB2-low versus RHOBTB2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOBTB2→partner) and Y-score (partner→RHOBTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal transport →	+0.059	+1.121	<.001	<.001	3	10
URINARY_TRACT	Schwann cell differentiation →	+0.155	+1.742	<.001	.001	3	10
SKIN	Vacuole fusion →	+0.104	+0.952	<.001	<.001	3	10
BLOOD_Myeloma	Endocytic recycling →	+0.055	+1.169	<.001	<.001	3	9
LARGE_INTESTINE	Negative regulation of smoothened signaling pathway →	+0.053	+1.027	<.001	<.001	3	9
URINARY_TRACT	Schwann cell development →	+0.142	+1.703	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,291 associations by consensus.

Endosomal transport by RHOBTB2 expression — SKIN

Explore this box plot interactively →